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1.
Rev. venez. oncol ; 24(1): 34-41, ene.-mar. 2012.
Article in Spanish | LILACS | ID: lil-704407

ABSTRACT

Dada la importancia del cáncer cervical y la infección por VPH como problemas de salud pública en el mundo, diversas investigaciones se han enfocado en el desarrollo de vacunas profilácticas y terapéuticas para la prevención y/o tratamiento de esta enfermedad. Dentro de las estrategias terapéuticas, la terapia génica se proyecta como una estrategia clínica poderosa para la eliminación o regresión de las lesiones cancerosas a corto y mediano plazo. La presente es una revisión sobre los progresos de estas investigaciones


Given the importance of the cervical cancer and HPV infection as a public health problem in the entire world, several studies have focused on the development of the prophylactic and the therapeutic vaccines for the prevention and for the treatment of this disease. Among the therapeutic strategies, the gene therapy is projected as a powerful clinical strategy for elimination or regression of cancerous lesions in the short and medium term. This is a review on the progress of these investigations


Subject(s)
Infant, Newborn , Papillomavirus Infections/prevention & control , Papillomavirus Infections/therapy , Uterine Cervical Neoplasms/pathology , Uterine Cervical Neoplasms/prevention & control , Uterine Cervical Neoplasms/therapy , Genetic Therapy/methods , Papillomavirus Vaccines/therapeutic use , Medical Oncology , Public Health
2.
Rev. venez. oncol ; 22(1): 32-38, ene.-mar. 2010.
Article in Spanish | LILACS | ID: lil-571101

ABSTRACT

Se presenta una revisión sobre la relación entre el virus de papiloma humano y el cáncer cérvico uterino, haciendo énfasis en el papel etiológico de la infección viral durante el desarrollo de malignidad, los posibles factores y cofactores involucrados y la importancia clínica de este conocimiento en el diagnóstico y tratamiento de dicha patología, considerada mundialmente como un problema de salud pública.


This is a review about the relationship between human papillomavirus and the cervical cancer, with emphasis on the etiological role of the viral infection during the development of malignancy, the possible factors and the cofactors involved and the importance of this knowledge in clinical diagnosis and treatment of this kind of pathology, seen in worldwide as a public health problem.


Subject(s)
Humans , Female , Papillomavirus Infections/etiology , Papillomavirus Infections/transmission , Uterine Cervical Neoplasms/pathology , Uterine Cervical Neoplasms/prevention & control , Carcinoma, Squamous Cell/pathology , Risk Factors , Precancerous Conditions/pathology , Medical Oncology
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